Endocrine Abstracts

Introduction: Glucocorticoids are hormones that are used extensively in medicine for their anti-inflammatory and immunomodulatory effects. New onset diabetes mellitus is a frequent complication and is the result of an activation of glucocorticoid receptors which stimulate hepatic gluconeogenesis, adipose tissue lipolysis and increase the insulin resistance.Case presentation: We present a case of a 49-year-old Ukrainian female who in 2015 started having h...

We present the case of a 36-year-old female with a focal neonatal hyperinsulinism diagnosed at birth in a context of hypoglycemia that was resistant to Diazoxide treatment. A subtotal pancreatectomy was performed and histology showed a focal hyperinsulinism. The mutation of ABCC8 was not searched at this point. The patient developed an insulin dependent diabetes at the age of 9 and required an insulin pump. In 2017 the patient was planning a pregnancy so she consulted a geneti...